The Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR) Omnibus Solicitations are intended to support small business innovation research across a broad spectrum of topic areas.
U.S. small businesses that have the research capabilities and technological expertise to contribute to the research and development missions of the awarding components identified in the Omnibus Solicitation are encouraged to submit investigator-initiated SBIR & STTR grant applications in response to the identified topics. Applicants may also consider other areas of research within the mission of any of the awarding components and submit an SBIR & STTR application
Small business concerns that are majority-owned by multiple venture capital operating companies (VCOCs), hedge funds and/or private equity firms continue to be eligible to apply to the CDC and NIH SBIR program and compete for up to 15% and 25% respectively of each agency's SBIR set-aside.
Omnibus Solicitation Opportunities
This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.
- SBIR Program: PA-27-100 (Clinical Trial Optional)
- NIH, CDC, and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44])
- Standard Receipt Dates: September 5, 2026; January 5, 2027; April 5, 2027
- STTR Program: PA-27-102 (Clinical Trial Optional)
- NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42])
- Standard Receipt Dates: September 5, 2026; January 5, 2027; April 5, 2027
Application Resources:
- Online HTML Application Guide
- SF424 (R&R) Application Guide for SBIR/STTR Grant Applications (Version i)
- Annotated SF424 SBIR/STTR Form Set
- NIH Matchmaker - Use NIH Matchmaker to conduct keyword searches on a particular topic area to identify NIH Institutes or Centers (ICs) that have previously funded research area.