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Leading small business innovation and commercialization in the fight against cancer
What are SBIR & STTR?

The goal of the NCI is to eliminate the suffering and death due to cancer. The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs are NCI's engine of innovation for developing and commercializing novel technologies and products to prevent, diagnose, and treat cancer.

The SBIR & STTR Programs are one of the largest sources of early-stage technology financing in the United States. We welcome entrepreneurs and small business leaders to this website to explore grant and contract funding opportunities and a new spirit of collaboration with the NCI.

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Tips for Applying

Online Resources Video Screen Shot
Click here to view online resources that help small businesses prepare their grant applications and contract proposals. Resources include annotated SBIR grant applications, videos with tips for applying for NCI SBIR & STTR funding, and guidance on the electronic submission process.

While there are no actual examples of SBIR contract applications available, the slides from these recent SBIR & STTR Program information sessions provide valuable insight into the application process. In addition, visit the How to Apply section on the SBIR Web site for examples of SBIR grant applications. Please note that all contract applications must be submitted via paper application.

Latest Announcements

*NEW* NCI SBIR Bridge Funding Available - Up to $3M per Small Business Award: Apply Today

The SBIR Phase II Bridge Award is designed to support the next stage of development for previously funded NIH-wide SBIR Phase II projects in the areas of cancer therapies, diagnostics, and cancer imaging technologies. The NCI intends to commit up to $10 million in fiscal year 2010 to fund up to ten applications. The purpose of this award is to address the funding gap known as the “Valley of Death” between the end of the SBIR Phase II award and the subsequent round of financing needed to advance a product or service toward commercialization. Click here to read more about the SBIR Phase II Bridge Award.
Application receipt date:
March 1, 2010

Letter of Intent receipt date:
February 1, 2010


*NEW* NCI SBIR & STTR Funding Available for Image-Guided Cancer Interventions

Grant funding opportunities are now available to eligible small businesses for the development and commercialization of novel image-guided interventions to prevent, diagnose, and treat cancer.
Learn more about 2010 Grant funding
Application receipt dates: April 5; August 5; December 5, 2010


NCI SBIR Program Announces Phase II Bridge Awardees

The NCI’s SBIR Development Center is pleased to announce the award of four new Phase II Bridge Awardees. The Bridge Award is a new funding opportunity for promising cancer therapies and imaging technologies that more than triples the amount of funding available through the NCI SBIR Program. [Read more]





Employment Opportunities

NCI is seeking highly motivated applicants with strong industry or venture capital experience for positions within the NCI SBIR Program. Click here to learn more.