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Leading small business innovation and commercialization in the fight against cancer
What are SBIR & STTR?

The goal of the NCI is to eliminate the suffering and death due to cancer. The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs are NCI's engine of innovation for developing and commercializing novel technologies and products to prevent, diagnose, and treat cancer.

The SBIR & STTR Programs are one of the largest sources of early-stage technology financing in the United States. We welcome entrepreneurs and small business leaders to this website to explore grant and contract funding opportunities and a new spirit of collaboration with the NCI.

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Michael Weingarten, Director of the NCI SBIR & STTR Programs discusses how the program began and why it is so important to improving cancer treatments and care for patients.



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Program Announcements

2012 NCI SBIR Investor Forum Date Announced

Save the Date! NCI SBIR will host the 2012 Investor Forum on April 18 at Agilent Technologies in Santa Clara, CA. The NCI SBIR Investor Forum is designed to connect promising NCI SBIR companies with investors and strategic partners. Click here to learn more about the Investor Forum.


NEW: $10M Available through NCI SBIR Phase II Bridge Award – Apply Today!

The NCI is offering $10M in funding for up to ten new awards in FY2012 for small businesses that seek additional funding to support the next stage of development for previously funded NIH-wide SBIR Phase II projects in the areas of cancer therapeutics, imaging technologies, interventional devices, diagnostics, and prognostics. Read more about the Phase II Bridge Award and how to apply.



Share Your Company's Success Story

The NCI SBIR Development Center is interested in learning more about how SBIR & STTR funding is helping your company to achieve its cancer research goals and business objectives. Please click here to fill out a 'Share Your Story' form, and let us know about any developments with your NCI SBIR- or STTR-funded projects. Learn more about how other successful NCI SBIR & STTR companies are using their funding awards to advance cancer research.



Tips for Applying: Granting You Success

NCI SBIR & STTR Leadership Discuss How to Tap into Available Resources

NCI SBIR Development Center Director Michael Weingarten and Program Director David Beylin participated in a live webinar hosted by the NCI's Office of Cancer Centers, in which they provided an overview of the NCI SBIR & STTR Programs and initiatives to help small businesses further commercialize their innovations. Additionally, SBIR grantee James Olson shared how he strategically leveraged the SBIR Program to help raise investor funding and advance his company's cancer technology to the next stage of development. Please click here to view the presentation from this webinar.


Nature Biotechnology Publishes Article on the SBIR & STTR Programs

In an article published in Nature Biotechnology, SBIR & STTR Development Center staff discuss the application process and provide tips for applying for funding through the SBIR & STTR Programs.

Latest Announcements

NCI SBIR Investor Forum, April 18, 2012, Santa Clara, CA
Learn more about the 2012 NCI SBIR Investor Forum




NEW: NCI SBIR Phase II Bridge Award Funding

$10M in funding available for up to ten awards in FY2012 to support the next stage of development for previously funded NIH-wide SBIR Phase II projects. Learn more about the Bridge Award.

Receipt Date: March 27, 2012




NCI SBIR & STTR Grant Funding Available for:

  • Cancer Diagnostic and Therapeutic Agents Enabled by Nanotechnology
  • Technology Development for the Detection and Evaluation of Chemical and Biological Carcinogens
  • Technology for the Detection and Characterization of Low Abundance Proteins, Peptides, or micro RNAs
  • Image-Guided Cancer Interventions

View a complete list of funding opportunities.




NIH Announces SBIR Niche Assessment Program for Phase I Awardees

The NIH SBIR is pleased to announce the launch of the 8th year of the National Institute of Health's SBIR Niche Assessment Program for NCI SBIR Phase I awardees, a nationwide program funded by NIH to help jump-start the commercialization efforts of SBIR Phase I awardees. Please click here for more information about the program and how to apply.




NCI Provocative Questions Website

NCI Director Harold Varmus launched a website as part of the Provocative Questions Initiative. The Provocative Questions website allows individuals to submit questions, rank questions submitted by others, comment on questions, and participate in an online discussion of the initiative.


Employment Opportunities

NCI is seeking highly motivated applicants with strong industry or venture capital experience for positions within the NCI SBIR Program. Click here to learn more.