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NCI Seeks Your Input on Cancer Research and Diversity!
May 13, 2021

NCI has issued new Request for Information (RFI) on cancer health disparities research and diversity in workforce. Click the notification number below for full solicitation.

  • Seeking stakeholder input on enhancing cancer health disparities research: NOT-CA-21-066
  • Seeking stakeholder input on enhancing diversity and inclusion in the cancer research workforce: NOT-CA-21-067
Two BRAND NEW Funding Opportunities
December 21, 2020

NCI SBIR has released two brand new funding opportunities for early career researchers and out-of-the-box thinkers!

Visit the funding pages to get more information.

View FDA Resources!
November 12, 2020

We worked with the experts at the FDA to put together a curated list of helpful resources! Visit our FDA Resources page to get started. 

NCI SBIR Virtual MedTech Showcase
August 4, 2020

NCI SBIR is hosting our first Virtual MedTech Showcase on September 9 and 10, 2020. Investors and strategic partners are invited to virtually connect with NCI SBIR-funded MedTech companies. Register today!

FY21 Contract Solicitation
August 3, 2020

2021 SBIR Contract Solicitation is now available! Check out Current Contracts page to view this year's 17 topics proposed by the National Cancer Institute.

New Supplement for Technologies Adapted for COVID-19
April 9, 2020

The NCI SBIR Development Center is issuing a Notice of Special Interest (NOSI) to highlight the urgent need for the development of prophylactic, therapeutic and diagnostic for Coronavirus Disease 2019 (COVID-19). This supplement is open to current SBIR- and STTR-funded projects. For more information, visit the award page.

COVID-19 Updates
March 18, 2020

Due to the potential impact of the declared public health emergency caused by the 2019 Novel Coronavirus (COVID-19), the NIH has issued multiple guide notices, incluing notice on late applications. If your business is affected by COVID-19, check the list of available measures on our Notices Page.

New Administrative Supplement Available!
March 5, 2020

New opportunities for current Phase I SBIR companies! Get supplement funding to move your project to the next stage! Check the new Notice of Special Interest today.

FY2020 I-Corps at NIH Dates Announced!
August 20, 2019

You can now find application deadlines and cohort dates for I-Corps at NIH 2020 cohorts! Check our I-Corps at NIH page for more information.

FY20 Contracts Solicitation
June 24, 2019

Now available: Pre-solicitation to FY2020 SBIR Contract Solicitation. Click here to see the solicitation and the 16 SBIR contract topics from the Natonal Cancer Institute!

SBIR Direct-to-Phase II
October 16, 2018

Recent legislation has re-instated the SBIR Direct-to-Phase II provision. Applicants can now apply for Direct-to-Phase II for SBIR Omnibus Solicitation, as well as targeted funding opportunities. For more information, please check Guide Notices NOT-OD-19-019 (Omnibus), NOT-CA-19-002 (IMAT), and NOT-CA-19-003 (Low Resource Settings)

No Longer Accepting SAM-related Late Submission
August 3, 2018

NIH will no longer accept late applications due to delays in SAM registration or renewal, as GSA is no longer requiring entities to have an approved Entity Administrator notarized letter on file before their registration is activated. For the full announcement, please refer to NOT-OD-18-215.

FY19 Contract Solicitation Now Available!
July 19, 2018

Find out more about this year's Contract Solicitation and the 15 NCI topics on our Current Contracts page!

New Admin Supplement for Workforce Diversity
June 22, 2018

Companies with active SBIR/STTR funding can apply for additional funding through the new Administrative Supplement for Workforce Diversity. For eligibility and other information, check out PA-18-837

New Funding Opportunities
May 29, 2018

Are you developing an affordable cancer tech for low-resource settings? You can now apply for the new funding opportunity on global health! SBIR: PAR-18-801 & STTR: PAR-18-802

FY19 Phase IIB Bridge Award Solicitation Now Available!
February 15, 2018

The new Phase IIB Bridge Award announcement is now available! Find more information about the program on the Bridge page or RFA-CA-18-011

January 22, 2018

As a result of the current Federal government funding situation, the information on this website may not be up to date or acted upon.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit

Updates regarding government operating status and resumption of normal operations can be found at

Updated SBIR/STTR Omnibus Solicitations for 2018
January 16, 2018

HHS has issued 4 new funding opportunity announcements (FOAs) for SBIR/STTR omnibus solicitations with FORMS-E and clinical trials policy update. Check out all four FOAs on Omnibus Solicitations page

Applicant Assistance Program (AAP)
January 5, 2018

The SBIR/STTR Applicant Assistance Program (AAP) is aimed at helping eligible small R&D businesses and individuals successfully apply for Phase I SBIR/STTR funding. Find out more about this FREE program on the AAP Page.

Supplement for Diversity Recruiting
November 16, 2017

Now available: New supplement funding for recruiting and supporting individuals of underrepresented racial/ethnic groups, with a disability, or from disadvantaged backgrounds. Check program announcement or program page for more information.

Deadline Extended for SBIR Contract Solicitation!
October 18, 2017

The due date for FY18 SBIR Contract Solicitation has been extended by a week! Submit your application by Friday, October 27, 2017 5 PM Eastern Daylight Time. 

Establish strong business strategy
October 12, 2017

The new funding opportunity announcement (PA-18-314) for I-Corps at NIH entrepreneurship program is now available! Find more information on I-Corps at NIH webpage

Be ware of scam emails!
October 5, 2017

System for Award Management (SAM) registration is FREE. You can always get free system and technical help through our supporting Federal Service Desk. In addition, Procurement Technical Assistance Centers (PTACs) can provide free help with your SAM Registration – and other government contracting issues. Read more: HERE and HERE.

NIH Natural Disaster Policy
August 29, 2017

If you are in a region affected by Hurricane Harvey and plan to submit an SBIR or STTR funding application for the deadline of 9/5/2017, please note the NIH Natural Disaster Policy (NOT-OD-17-106.)

Michael Weingarten Explains SBIR Contracts
August 25, 2017

NCI SBIR Director talks about NCI SBIR Contracts Solicitation in this interview with Cancer Currents. CLICK TO READ


FY18 SBIR Contract Topics Now Available!
July 18, 2017

FY18 HHS SBIR Contracts Solicitation is now available. Visit our Current Contracts page to view the list of 12 new contract topics.

2017 Omnibus Solicitations Now Available
June 6, 2017

The new Funding Opportunity Announcements (FOA) for 2017 Omnibus Soliciation are now available for both SBIR and STTR! Next receipt date is September 5, 2017. For more information, visit Omnibus Solicitations page.

New FOA for Bridge Award!
April 12, 2017

SBIR Phase IIB Bridge Award for 2017 now available! (RFA-CA-17-024) Application receipt date is July 6, 2017. For more information, visit our Bridge Award page

Join us in Houston, TX!
March 15, 2017

Meet with NCI SBIR Team Leader Greg Evans at JLabs TMC on April 12! One-on-one meeting available. [MORE INFO]

We're Going to AACR 2017!
February 28, 2017

Meet with program staff at AACR 2017! We'll be holding a Panel Session on commercialization, as well as Meet-the-Expert sessions at booth #1407. [MORE INFO]

New FOAs for Single Cell Analysis
February 9, 2017

New FOAs: Development of Highly Innovative Tools and Technology for Analysis of Single Cells (PA-17-147/148) [MORE INFO]

Sign Up for Email Updates
January 30, 2017

Submit your email in the box below to receive latest news and updates from NCI SBIR Development Center.

NEW I-Corps at NIH FOA Now Available!
December 27, 2016

The 2017 I-Corps at NIH FOA is now available. Next deadline=Jan 9, 2017! [MORE]

Webinar: I-Corps at NIH
November 28, 2016

Join us for I-Corps at NIH info webinar on Dec 8, 2016, 12:30 - 1:30 PM! [REGISTER]

Pilot Program Deadline Fast Approaching!
November 11, 2016

Submit applications for Direct-to-Phase-II pilot programs by Jan 5, 2017! [INFO]

Meet with NCI SBIR at RSNA 2016
November 11, 2016

Meet with NCI SBIR staff at RSNA 2016 (Nov 27-Dec 2). [INFO]

We're headed to PMWC 2017!
October 27, 2016

Find out more about NCI SBIR sessions at PMWC 2017! 

Check New Notices for Funding and RFI
October 24, 2016

New NIH notices on RFIs and direct cost now available on NOTICES page.

Got Qs for I-Corps at NIH?
October 11, 2016

Join us for an "open-air" Q&A session for I-Corps at NIH program. [SIGN UP]

Amendment to FY17 Contract Solicitation
September 23, 2016

Q&A Amendment to FY17 Contract Solicitation

New Notices for NIH Funding Applications!
September 7, 2016

Two new notices on NIH funding applications now available. Notices are valid for applications submitted on or after Jan 25, 2017. [MORE]

NCI SBIR is Coming to Your City!
August 30, 2016

This September, we are going to IN, CA, TX, NC, MD, WA, and MORE!

FY2017 Contract Webinar Recording Now Available
August 30, 2016

CLICK HERE for resources from Aug 24 NIH Contracts Webinar.

Indianapolis & San Diego on Sept 1!
August 22, 2016

Two outreach events on September 1. Find out more on EVENTS

FY2017 Contract Webinar
August 8, 2016

Sign up for NIH webinar on August 24 on PHS 2017-1 soliciation. [MORE]

Meet with NCI SBIR in Cambridge, MA
August 8, 2016

Meet with NCI SBIR program staff on Wednesday, August 31 for an information session on new and current funding opportunities, NCI SBIR resources, and application tips! [MORE]

Info Session in LA
August 8, 2016

Meet with NCI SBIR on September 6, 2016 for info session on funding opportunities! [MORE]

NIH Small Business Workshop in TX
August 8, 2016

Join NCI SBIR for a two-day NIH Multi-IC Small Business Workshop in San Antonio, TX on September 7-8, 2016. [MORE]

We'll be in San Francisco!
July 26, 2016

Meet with NCI SBIR director and program manager in San Francisco, CA on August 8, 2016! [LEARN MORE]

Are you in Boston, MA?
July 26, 2016

Join us @ JLABS in Cambridge on August 31! [DETAILS HERE]

Join Us for Free Webinar on SBIR for Women in Biotech!
July 11, 2016

Join NCI SBIR, NCATS, NINDS, and BIO for a webinar on SBIR and STTR funding for women entrepreneurs and researchers in biotech on July 14, 2016! Register Today Exit Disclaimer

Tune into NIH SBIR Webinar at KY Innovation Centers!
July 6, 2016

 “NIH Day” on-site webinar from 9 AM on Monday, July 11, 2016 at your nearest Kentucky Innovation Network Offices across the state. NCI SBIR Program Director Deepa Narayanan will be giving a presentation, as well as at the one-on-one sessions from 2:00 to 4:00 PM

Meet with NCI SBIR at HHS SBIR/STTR Conference!
June 14, 2016

We will be at the 18th Annual HHS SBIR/STTR Conference from November 15 to 17! Meet with us in Orlando, Florida and get your SBIR/STTR questions answered by NCI SBIR program staff!

2016 Omnibus Grant FOAs are Now Available!
June 6, 2016

The 2016 Omnibus Grant FOAs for SBIR and STTR are now available! (Visit Page) For detailed information, check out the notice (NOT-OD-16-103) or the omnibus solicitation page on our website.

Meet with NCI SBIR at ASCO 2016!
May 31, 2016

Join us at Booth #5053 for a Meet-the-Expert session with NCI SBIR program director Deepa Narayanan on June 6, 2016.

Visit our events page for more details.


Join Us at BIO 2016!
May 31, 2016

NCI SBIR is going to BIO 2016! Find NCI SBIR at booth #7149 or any of our Meet-the-Expert sessions on June 7 & 8. 

Session details are available on our events page.

NCI SBIR FRAC Workshop 2016
May 16, 2016

NCI SBIR is hosting FRAC Workshop! It's a two-day workshop focusing on federal resources to accelerate commercialization for current SBIR/STTR awardees. Find out more: FRAC 2016 

Register now for FRAC 2016!
April 5, 2016

The registration for the NCI SBIR FRAC Workshop is now open! Register now and secure 1:1 interviews with speakers and program directors!

For more information, please visit the FRAC page.

Novel & Emerging Cancer Tech?
March 31, 2016

Do you have novel and emerging cancer technologies? Then consider applying for the Innovative Molecular Analysis Technology Development for Cancer Research and Clinical Care (SBIR-IMAT) solicitation!

The receipt date is May 27, 2016.

For detailed information, please visit our SBIR-IMAT page


NCI SBIR is going to AACR 2016!
March 22, 2016

Meet with us at Booth #1012!


For more information on SBIR sessions at AACR 2016, please check our events page (CLICK HERE). 

I-Corps at NIH - next deadline March 21!
February 23, 2016

**Application budgets have been updated (Feb 18): NOT-CA-16-029

Applications for the June - August 2016 cohort in I-CorpsTM at NIH are due March 21, 2016.


The NIH hosted an informational webinar on the I-Corps™ at NIH program on Thursday, November 12 with details about the program, eligibility, benefits, and how to apply. Materials from the previous webinar, including slides and recordings are now available website:

Following the success of the 2014 pilot cohort, NIH is offering this entrepreneurial training program across 14 Institute/Centers at the NIH and CDC to support NIH/CDC SBIR/STTR funded small businesses to accelerate the translation of innovations from the lab to clinical practice.

The I-Corps™ at NIH, part of President Obama’s Strategy for Innovation, is modeled after the successful I-Corps™ at NSF and will be leveraged to support biomedical innovation and translation, with the goal of expediting the development and commercialization of a range of technologies to address the leading causes of death and disability in the United States. I-Corps™ participants will receive lessons on how to build a scalable business model as well as entrepreneurial trainings, and mentorship opportunities.  In addition, modest funding will be provided to teams to assist them in translating their ideas from the lab into a viable product on the market and to help them avoid common failure points.

View the funding opportunity announcement and call for applications to apply: PA-16-019

For more information or questions on the I-Corps™ at NIH program, please visit


Submit Your Applications for FY 2017 Phase IIB Bridge Award
February 18, 2016

The National Cancer Institute plans to commit $10 million for up to 10 new awards in FY2017. View the Funding Opportunity Announcement (FOA) for Phase IIB Bridge Award: RFA-CA-16-008

If you would like to be considered for the award, submit your applications to by July 13, 2016. 



You can also learn more about the award on our Phase IIB Bridge Award page.

New Investor Initiatives for NCI SBIR/STTR Awardees
February 10, 2016

Investor Initiatives for NCI SBIR companies

DEADLINE EXTENDED: submit your application by 5 PM on Wednesday, February 24, 2016.

NCI SBIR/STTR Companies! Do you want to put your technology in front of investors? Do you want to get connected to potential partners? If so, Apply Now

One application is intended to be used for all of NCI’s investor initiatives starting in late summer 2016 through spring of 2017.
For additional details and instruction, view the Application Guide for NCI Investor Initiatives or our Investor Initiatives webpage.

I-Corps at NIH Q&A Office Hour
February 9, 2016

The NIH is holding an I-Corps Office Hour Q&A session with an I-Corps instructor on February 18. If you would like to get your I-Corps questions answered, please register here Exit Disclaimer.


I-Corps at NIH Q&A Office Hour [RSVP NOW Exit Disclaimer]

Thursday, February 18, 2016 12:00 - 12:30 PM EST

Panel: Edmund Pendleton, Lead Instructor, NIH & NSF I-Corps; Assistant faculty director, NSF I-Corps

Find NCI SBIR Staff at AACR 2016!
February 6, 2016

The NCI SBIR team will be at the AACR 2016! Find us at kiosk #1012.

Notice Clarifying SBIR Direct-to-Phase II Elibigility Criteria
January 12, 2016

The purpose of this Notice is to clarify the types of applications which can be submitted to the National Institutes of Health Small Business Innovation Research (NIH SBIR) Direct-to-Phase II pilot funding opportunity announcement PAR-14-088. The NIH Direct-to-Phase II program will accept Phase II submissions regardless of the funding source for the Phase I-like proof of principle work on which the proposed Phase II research is based.

Carefully review the Notice language for complete details:

NIH SBIR/STTR Workshop at RSNA 2015!
November 12, 2015

Join us at our upcoming workshop Exit Disclaimer, NIH SBIR/STTR Program To Support Innovative Commercial Product Development By Small Businesses and Academic Partners. Program staff from across NIH will provide tailored funding information for innovators from the small business and academic communities who are interested in commercializing their technology and getting it into the clinic.  You will need to add this workshop to your program when you register for RSNA Exit DisclaimerRegistration for this workshop is included in the cost of the RSNA registration.

View more information on our events page.

NIH Niche Assessment Program Available for Phase I Awardees
November 2, 2015

NIH Niche Assessment Program for Phase I Awardees

Program is currently OPEN for NIH SBIR/STTR Phase I Awardees!

The National Institutes of Health (NIH) Niche Assessment Program for HHS (NIH, CDC, FDA) is a nationwide program funded by NIH to help jump-start the commercialization efforts of active SBIR & STTR Phase I awardees and Phase I Fast-Track awardees. NIH has contracted with Foresight Science and Technology to perform Technology Niche Analyses® (TNA®) for 177 HHS SBIR & STTR Phase I awardees.

STTR awardees are eligible to participate in this program.

The NIH Niche Assessment Program can help your company's commercialization efforts by:

  • Providing market insight and data to strategically position your technology in the marketplace.
  • Assisting in commercialization plan development for Phase II applications.
  • Introducing small businesses to potential partners.
  • For a full description of the program, please review the NIH Guide Notice at: NOT-OD-16-013.

To participate in the program, complete the registration form.  

For more information, visit:

Deadline Extended! - HHS SBIR Contract Solicitation now due 10/22
October 21, 2015

The original FY2016 Contract Topic Solicitation due date has been extended to Thursday, October 22 at 5:00pm EDT.

New Submission Process: There is a new electronic submission process for all proposals. Applicants must use the Contract Proposal Submission (eCPS) website to submit their proposal.  No other method of proposal submission is permitted. Instructions for electronic submission are provided in the solicitation.

For more information about the solicitation, visit our Contracts page.

Get Your Questions Answered on 11/18!
October 13, 2015

The National Cancer Institute Small Business Innovation Research and Small Business Technology Transfer Programs (NCI SBIR & STTR) invite you to a presentation by the NCI SBIR Development Center on November 18 from 2:00pm to 4:00pm EST. Program staff will discuss the SBIR and STTR Programs, which fund and support small biomedical technology companies, as well as funding opportunities, and Tips on Applying.

The next Standard Receipt Date is January 5, 2016. Start your applications early and feel free to ask us any questions about current Grant Opportunities during the Q&A portion of the webinar.

Register today!


ASSIST Program Available to Small Businesses
September 25, 2015
Have you ever wanted a system that checks your HHS SBIR/STTR grant application for errors BEFORE you submit it? 
ASSIST (Application Submission System & Interface for Submission Tracking) is NIH's online system for the preparation, submission, and tracking of grant applications through to NIH. Small businesses may now use ASSIST to submit SBIR and STTR grant applications. ASSIST is not required, so small businesses can still apply using the’s downloadable forms method.
SBIR Technology Transfer Funding Opportunity Now Available!
September 25, 2015

This Funding Opportunity Announcement encourages Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) for projects to transfer technology out of the NIH intramural research labs into the private sector. If selected for SBIR funding, the SBC will be granted a royalty-free, non-exclusive patent license agreement for internal research use for the term of and within the field of use of the SBIR award to technologies held by NIH with the intent that the SBC will develop the invention into a commercial product to benefit the public.

Standard Due Dates Apply. The next receipt date is January 5, 2016.

Funding Available through SBIR & STTR Omnibus Solicitation & More
September 1, 2015

NOTE SPECIAL DUE DATE SEPTEMBER 8, 2015 (September 5 is a weekend and September 7 is a Federal Holiday)

The deadline is approaching - submit your investigator-initiated proposals to the SBIR & STTR Omnibus Solicitations.  U.S. small businesses with the research capabilities and technological expertise identified in the FY2015 Omnibus Solicitation are encouraged to submit investigator-initiated grant applications for the National Cancer Institute’s high-priority research areas. Applicants may also propose other areas of research within the mission of NCI. Learn more about the 2015 Omnibus Solicitation.

September 8 is also the due date for PA-13-140: Development of Highly Innovative Tools and Technology for Analysis of Single Cells. Learn more at

You can also read more about funding opportunities from NCI and NIH.

Receipt dates: September 8, 2015; January 5, 2016; April 5, 2016

HHS SBIR Contract RFP Informational Webinar Materials Now Available!
August 28, 2015

HHS held a pre-proposal conference, via webinar, on August 13, 2015 at 2:00 PM Eastern Daylight Time.  This informational webinar covered topics in this solicitation, as well as the new electronic contract proposal submission (eCPS) website.

For more information on the FY2016 Contract Solicitation, please visit our Contracts page.

Learn how the new NIH Resubmission Policy affects SBIR and STTR applications
June 4, 2015

Before April 16, 2014, NIH permitted one resubmission (A1) of an unfunded application. The extension on the NIH grant number could follow the pattern (A0, A1). A first-time submission is informally referred to as an A0, and the first resubmission is known as an A1. Any virtual A2s would be flagged by the NIH Center for Scientific Review.

For all application due dates after April 16, 2014, following an unsuccessful resubmission (A1) application, applicants may submit the same idea as a new (A0) application for the next appropriate new application due date.

Resubmissions (A1) must be submitted within 37 months of the new (A0) application. For more details on the Resubmission Policy, visit the NCI SBIR Resources for Applicants webpage.

Important Change to SBIR & STTR Grant Due Dates
March 10, 2015

The National Institutes of Health is changing its Standard Due Dates for SBIR & STTR grant applications, in an effort to respond to the needs of the small business community, congressional mandates, and the Scientific Management Review Board (SMRB) recommendations.

This modification, coupled with other internal changes, will shorten the response time to SBIR/STTR grant applicants on the status of their applications, and will enable the team to make funding recommendations and awards sooner. This will help improve the applicant experience and drive innovative technology from research to market faster and more efficiently.

This change affects all SBIR & STTR Funding Opportunity Announcements (FOAs) using Standard Due Dates. The new Standard Due Dates are September 5, January 5, and April 5.

New Late Submission Policy
January 25, 2015

The policy for late applications has been updated and revised. Please review NOT-OD-15-039 to learn more and for examples of reasons that late applications may be accepted. This late submission policy will be effective for all applications submitted on or after January 25th, 2015.

AdvaMed 2014 Selects NIH Companies as Emerging Growth Company Scholars
September 3, 2014

The NCI SBIR Development Center and NIH are proud to announce that the Emerging Growth Company Scholarships have been awarded to NCI/NIH-funded companies to attend the AdvaMed 2014 meeting this October 6-8, 2014 in Chicago, IL.

The RCT Grand Prize goes to Surgisense Corporation.
The Aon Midwest MedTech Scholar circle includes Lucigen Corporation (WI).
NIH Scholars – 12 complimentary Company Presentations and complimentary full-access registrations for recipients of SBIR funding from five participating Institutes and Centers: National Cancer Institute (NCI); National Heart, Lung, and Blood Institute (NHLBI); National Institute of Allergy and Infectious Diseases (NIAID); National Institute of Biomedical Imaging and Bioengineering (NIBIB); and National Institute of Neurological Disorders and Stroke (NINDS).